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1

Synthesis and biological evaluation of 1-(2,4,5-trisubstituted phenyl)-3-(5-cyanopyrazin-2-yl)ureas as potent Chk1 kinase inhibitors

Gaoquan Li, Lisa A. Hasvold, Zhi-Fu Tao, Gary T. Wang, Stephen L. Gwaltney II, Jyoti Patel, Peter Kovar, Robert B. Credo, Zehan Chen, Haiying Zhang, Chang Park, Hing L. Sham, Thomas Sowin, Saul H. Ros

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 203 KB

english, 2006

2

EWS–FLI1 modulated alternative splicing of ARID1A reveals novel oncogenic function through the BAF complex

Selvanathan, Saravana P, Graham, Garrett T, Grego, Alexander R, Baker, Tabari M, Hogg, J Robert, Simpson, Mark, Batish, Mona, Crompton, Brian, Stegmaier, Kimberly, Tomazou, Eleni M, Kovar, Heinrich, Ü

Journal:

Nucleic Acids Research

Year:

2019

Language:

english

File:

PDF, 9.43 MB

english, 2019

3

Antibody-pHPMA functionalised fluorescent silica nanoparticles for colorectal carcinoma targeting

Lizoňová, Denisa, Majerská, Monika, Král, Vlastimil, Pechar, Michal, Pola, Robert, Kovář, Marek, Štěpánek, František

Journal:

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

4

Pyrazolo[3,4-d]pyrimidines as potent inhibitors of the insulin-like growth factor receptor (IGF-IR)

Robert D. Hubbard, Nwe Y. Bamaung, Fabio Palazzo, Qian Zhang, Peter Kovar, Donald J. Osterling, Xiaoming Hu, Julie L. Wilsbacher, Eric F. Johnson, Jennifer Bouska, Jieyi Wang, Randy L. Bell, Steven K.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 154 KB

english, 2007

5

Atomic force microscopic and encrustation studies of novel prospective polyisobutylene-based thermoplastic elastomeric biomaterials

Judit E. Puskas, Yaohong Chen, Prince Antony, Yongmoon Kwon, Milan Kovar, Robert R. Harbottle, Kathy De Jong, Peter R. Norton, Peter Cadieux, Jeremy Burton, Gregor Reid, Darren Beiko, James D. Watters

Journal:

Polymers for Advanced Technologies

Year:

2003

Language:

english

File:

PDF, 187 KB

english, 2003

6

Safety, Pharmacokinetics, and Biological Pharmacodynamics of the Immunocytokine EMD 273066 (huKS-IL2)

Ko, Yoo-Joung, Bubley, Glenn J., Weber, Robert, Redfern, Charles, Gold, Daniel P., Finke, Lothar, Kovar, Andreas, Dahl, Thomas, Gillies, Stephen D.

Journal:

Journal of Immunotherapy

Year:

2004

Language:

english

File:

PDF, 175 KB

english, 2004

7

Evaluation of a water-soluble contrast protocol for small bowel obstruction: A southwestern surgical congress multicenter trial

Moskowitz, Eliza E., McIntyre, Robert C., Burlew, Clay Cothren, Helmkamp, Laura J., Peltz, Erik D., Coleman, Julia R., Kovar, Alexandra, Truitt, Michael, Agrawal, Vaidehi, Onkendi, Edwin, Dev, Rushabh

Journal:

The American Journal of Surgery

Year:

2019

Language:

english

File:

PDF, 757 KB

english, 2019

8

Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent

Qun Li, Keith W. Woods, Akiyo Claiborne, Stephen L. Gwaltney, II, Kenneth J. Barr, Gang Liu, Laura Gehrke, R.Bruce Credo, Yu Hua Hui, Jang Lee, Robert B. Warner, Peter Kovar, Michael A. Nukkala, Nicol

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2002

Language:

english

File:

PDF, 181 KB

english, 2002

9

Poly [Benzobis Thiazole] (PBT)/SOL-GEL Microcomposites

Ross Haghighat, R., Kovar, Robert F., Lusignea, Ricahrd W.

Journal:

MRS Proceedings

Year:

1988

Language:

english

File:

PDF, 296 KB

english, 1988

10

Potent inhibitors of protein farnesyltransferase: Heteroarenes as cysteine replacements

Wang Shen, Stephen Fakhoury, Greg Donner, Kenneth Henry, Jang Lee, Haichao Zhang, Jerry Cohen, Robert Warner, Badr Saeed, Sajeev Cherian, Stephen Tahir, Peter Kovar, Joy Bauch, Shi-Chung Ng, Kennan Ma

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 319 KB

english, 1999

11

Direct Evidence That Iron Deprivation Induces Apoptosis in Murine Lymphoma 38C13

Kovar, Jan, Stunz, Laura L., Steward, Barbara C., Kriegerbeckova, Karin, Ashman, Robert F., Kemp, John D.

Journal:

Year:

1997

File:

PDF, 1.62 MB

1997

12

Debt and The Emerging Physician Workforce

Phillips, Julie, Peterson, Lars E., Fang, Bo, Kovar-Gough, Iris, Phillips, Robert L.

Journal:

Academic Medicine

Year:

2018

File:

PDF, 1.50 MB

2018

13

Thermosetting acetylene-terminated polyphenylquinoxalines

Robert F. Kovar, Gerhard F. L. Ehlers, Fred E. Arnold

Journal:

Journal of Polymer Science Part A: Polymer Chemistry

Year:

1977

Language:

english

File:

PDF, 869 KB

english, 1977

14

Polymer Therapeutics with a Coiled Coil Motif Targeted against Murine BCL1 Leukemia

Pola, Robert, Laga, Richard, Ulbrich, Karel, Sieglová, Irena, Král, Vlastimil, Fábry, Milan, Kabešová, Martina, Kovář, Marek, Pechar, Michal

Journal:

Biomacromolecules

Year:

2013

Language:

english

File:

PDF, 1.61 MB

english, 2013

15

Topical Antibiotic Spray in Contaminated Crush Wounds in Animals

Matsumoto, Teruo, Dobek, Arthur S., Kovaric, John J., Hamit, Harold F., Hardaway, Robert M.

Journal:

Military Medicine

Year:

1968

Language:

english

File:

PDF, 1.46 MB

english, 1968

16

Medical management of small preterm infants with symptomatic patient ductus arteriosus

Robert B. Cotton, Mildred T. Stahlman, Ilya Kovar, William Z. Catterton

Journal:

The Journal of Pediatrics

Year:

1978

Language:

english

File:

PDF, 622 KB

english, 1978

17

Self-Assembly of Peptide Porphyrin Complexes: Toward the Development of Smart Biomaterials

Kovaric, Brian C., Kokona, Bashkim, Schwab, Alexander D., Twomey, Margaret A., de Paula, Julio C., Fairman, Robert

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 85 KB

english, 2006

18

Polymer Carriers for Anticancer Drugs Targeted to EGF Receptor

Studenovsky, Martin, Pola, Robert, Pechar, Michal, Etrych, Tomas, Ulbrich, Karel, Kovar, Lubomir, Kabesova, Martina, Rihova, Blanka

Journal:

Macromolecular Bioscience

Year:

2012

Language:

english

File:

PDF, 312 KB

english, 2012

19

Randomized trial of early closure of symptomatic patent ductus arteriosus in small preterm infants

Robert B. Cotton, Mildred T. Stahlman, Harvey W. Bender, Thomas P. Graham, W.Z. Catterton, Ilya Kovar

Journal:

The Journal of Pediatrics

Year:

1978

Language:

english

File:

PDF, 400 KB

english, 1978

20

1-(5-Chloro-2-alkoxyphenyl)-3-(5-cyano- pyrazi-2-yl)ureas as Potent and Selective Inhibitors of Chk1 Kinase: Synthesis, Preliminary SAR, and Biological Activities

Wang, Gary T., Li, Gaoquan, Mantei, Robert A., Chen, Zehan, Kovar, Peter, Gu, Wendy, Xiao, Zhan, Zhang, Haiying, Sham, Hing L., Sowin, Thomas, Rosenberg, Saul H., Lin, Nan-Horng

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 269 KB

english, 2005

21

Discovery of 1,4-dihydroindeno[1,2-c]pyrazoles as a novel class of potent and selective checkpoint kinase 1 inhibitors

Yunsong Tong, Akiyo Claiborne, Kent D. Stewart, Chang Park, Peter Kovar, Zehan Chen, Robert B. Credo, Wen-Zhen Gu, Stephen L. Gwaltney II, Russell A. Judge, Haiying Zhang, Saul H. Rosenberg, Hing L. S

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 497 KB

english, 2007

22

Substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as multi-targeted inhibitors of insulin-like growth factor-1 receptor (IGF1R) and members of ErbB-family receptor kinases

Gary T. Wang, Robert A. Mantei, Robert D. Hubbard, Julie L. Wilsbacher, Qian Zhang, Lora Tucker, Xiaoming Hu, Peter Kovar, Eric F. Johnson, Donald J. Osterling, Jennifer Bouska, Jieyi Wang, Steven K.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.01 MB

english, 2010

23

The design and fabrication of autonomous polymer-based surface tension-confined microfluidic platforms

Michael J. Swickrath, Suresh Shenoy, J. Adin Mann, Jim Belcher, Robert Kovar, Gary E. Wnek

Journal:

Microfluidics and Nanofluidics

Year:

2008

Language:

english

File:

PDF, 581 KB

english, 2008

24

SPIE Proceedings [SPIE 1986 Quebec Symposium - Quebec City, Canada (Tuesday 3 June 1986)] Laser Radar Technology and Applications I - Single Longitudinal Mode Operation Of A Continuously Tunable High Pressure TE-CO2 Laser

Kovar, G, Piche, M., Belanger, P A., Cruickshank, James M., Harney, Robert C.

Year:

1986

Language:

english

File:

PDF, 2.36 MB

english, 1986

25

Physiologically-Based Pharmacokinetic (PBPK) Modeling Providing Insights into Fentanyl Pharmacokinetics in Adults and Pediatric Patients

Kovar, Lukas, Weber, Andreas, Zemlin, Michael, Kohl, Yvonne, Bals, Robert, Meibohm, Bernd, Selzer, Dominik, Lehr, Thorsten

Journal:

Year:

2020

File:

PDF, 824 KB

2020

26

A parallel implementation of the COLUMBUS multireference configuration interaction program

Matthias Schüler, Thomas Kovar, Hans Lischka, Ron Shepard, Robert J. Harrison

Journal:

Theoretical Chemistry Accounts: Theory, Computation, and Modeling (Theoretica Chimica Acta)

Year:

1993

Language:

english

File:

PDF, 1.31 MB

english, 1993

27

Organometallic derivatives of cymantrene. Formation of (fulvalene)hexacarbonyldimanganese

Kovar, Robert F., Rausch, Marvin D.

Journal:

Journal of Organic Chemistry

Year:

1973

Language:

english

File:

PDF, 803 KB

english, 1973

28

Synthesis and characterization of phenylated pyrazino-benzimidazophenanthroline polymers

Robert F. Kovar, F. E. Arnold

Journal:

Journal of Polymer Science Part A: Polymer Chemistry

Year:

1974

Language:

english

File:

PDF, 502 KB

english, 1974

29

Schaaf-Yang syndrome overview: Report of 78 individuals

McCarthy, John, Lupo, Philip J., Kovar, Erin, Rech, Megan, Bostwick, Bret, Scott, Daryl, Kraft, Katerina, Roscioli, Tony, Charrow, Joel, Schrier Vergano, Samantha A., Lose, Edward, Smiegel, Robert, La

Journal:

American Journal of Medical Genetics Part A

Year:

2018

Language:

english

File:

PDF, 1.46 MB

english, 2018

30

The Extremity/Mechanism/Shock Index/GCS (EMS-G) score: A novel pre-hospital scoring system for early and appropriate MTP activation

Kovar, Alexandra, Carmichael, Heather, McIntyre, Robert C., Mago, Jacob, Gladden, Alicia Heelan, Peltz, Erik D., Wright, Franklin L.

Journal:

The American Journal of Surgery

Year:

2019

Language:

english

File:

PDF, 473 KB

english, 2019

31

Profilin Regulates F-Actin Network Homeostasis by Favoring Formin over Arp2/3 Complex

Suarez, Cristian, Carroll, Robert T., Burke, Thomas A., Christensen, Jenna R., Bestul, Andrew J., Sees, Jennifer A., James, Michael L., Sirotkin, Vladimir, Kovar, David R.

Journal:

Developmental Cell

Year:

2015

Language:

english

File:

PDF, 3.70 MB

english, 2015

32

Cardiovascular Effects and Hemodynamic Mechanism of Action of the Novel, Nonpeptidic Renin Inhibitor A-74273 in Dogs

Wessale, Jerry L., Calzadilla, Samuel V., Boyd, Steven A., Baker, William R., Stein, Herman H., Kovar, Peter J., Barlow, Jennifer, Klinghofer, Vered, Mantei, Robert, Kleinert, Hollis D.

Journal:

Journal of Cardiovascular Pharmacology

Year:

1993

File:

PDF, 81 KB

1993

33

High Compressive Strength Ordered Polymer Fibers and Films Via Sol Gel Microcomposite Processing

Kovar, Robert F., Lusignea, Richard W., Haghighat, R. Ross, Pantano, Carlo, Thomas, Edwin L.

Journal:

MRS Proceedings

Year:

1989

Language:

english

File:

PDF, 1001 KB

english, 1989

34

Polymer Cancerostatics Targeted with an Antibody Fragment Bound via a Coiled Coil Motif: In Vivo Therapeutic Efficacy against Murine BCL1 Leukemia

Pechar, Michal, Pola, Robert, Janoušková, Olga, Sieglová, Irena, Král, Vlastimil, Fábry, Milan, Tomalová, Barbora, Kovář, Marek

Journal:

Macromolecular Bioscience

Year:

2017

Language:

english

File:

PDF, 1.25 MB

english, 2017

35

Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents

Stephen L. Gwaltney II, Hovis M. Imade, Kenneth J. Barr, Qun Li, Laura Gehrke, R.Bruce Credo, Robert B. Warner, Jang Yun Lee, Peter Kovar, Jieyi Wang, Michael A. Nukkala, Nicolette A. Zielinski, David

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 162 KB

english, 2001

36

Bookreviews

Pavel Kovář, Zdenka Neuhäuslová, Leoš Klimeš, V. Zelený, V. Novák, Marie Lhotská, František Krahulec, Jan Pokorný, Robert Neuhäusl, Tomáš Herben

Journal:

Folia Geobotanica

Year:

1990

Language:

english

File:

PDF, 804 KB

english, 1990

37

Poisson effect enhances compression force sensing with oxidized carbon nanotube network/polyurethane sensor

Slobodian, Petr, Riha, Pavel, Olejnik, Robert, Matyas, Jiri, Kovar, Michal

Journal:

Sensors and Actuators A: Physical

Year:

2018

Language:

english

File:

PDF, 2.64 MB

english, 2018

38

Novel sulfonate Derivatives: potent antimitotic agents

Stephen L. Gwaltney II, Hovis M. Imade, Qun Li, Laura Gehrke, R.Bruce Credo, Robert B. Warner, Jang Yun Lee, Peter Kovar, David Frost, Shi-Chung Ng, Hing L. Sham

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 138 KB

english, 2001

39

Study of the betulin molecule in a water environment; ab initio and molecular simulation calculations

Miroslav Pospíšil, Petr Kovář, Robert Vácha, Michal Svoboda

Journal:

Journal of Molecular Modeling

Year:

2012

Language:

english

File:

PDF, 465 KB

english, 2012

40

Self Assembly of Coiled-Coil Peptide−Porphyrin Complexes

Kokona, Bashkim, Kim, Andrew M., Roden, R. Claire, Daniels, Joshua P., Pepe-Mooney, Brian J., Kovaric, Brian C., de Paula, Julio C., Johnson, Karl A., Fairman, Robert

Journal:

Biomacromolecules

Year:

2009

Language:

english

File:

PDF, 2.61 MB

english, 2009

41

1,4-Dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: Extended exploration on phenyl ring substitutions and preliminary ADME/PK studies

Yunsong Tong, Akiyo Claiborne, Magdalena Pyzytulinska, Zhi-Fu Tao, Kent D. Stewart, Peter Kovar, Zehan Chen, Robert B. Credo, Ran Guan, Philip J. Merta, Haiying Zhang, Jennifer Bouska, Elizabeth A. Ev

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2007

Language:

english

File:

PDF, 170 KB

english, 2007

42

Evaluation of the Prehospital Massive Transfusion Activation Scoring System, Extremity-Mechanism-Shock Index-Glasgow Coma Score with Trauma Quality Improvement Program Data

Kovar, Alexandra, Carmichael, Heather L., McIntyre, Robert C., Velopulos, Catherine, Peltz, Erik, Wright, Franklin L.

Journal:

Journal of the American College of Surgeons

Year:

2019

File:

PDF, 193 KB

2019

43

Para-ordered polybenzimidazole

Robert F. Kovar, F. E. Arnold

Journal:

Journal of Polymer Science Part A: Polymer Chemistry

Year:

1976

Language:

english

File:

PDF, 696 KB

english, 1976

44

Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II

Petermann, Robert, Mossier, Birgit M, Aryee, Dave NT, Khazak, Vladimir, Golemis, Erica A, Kovar, Heinrich

Journal:

Year:

1998

Language:

english

File:

PDF, 390 KB

english, 1998

45

Gonadal and Adrenal Effects on Hepatic Epidermal Growth Factor Receptor Expression in a Murine Model*

SCOCCIA, BERT, KOVAR, PETER, BENVENISTE, ROBERT

Journal:

Year:

1991

Language:

english

File:

PDF, 875 KB

english, 1991

46

Topical antibiotic spray in contaminated crush wounds in animals

Matsumoto, T., Dobek, A. S., Kovaric, J. J., Hamit, H. F., Woolf, Robert M.

Journal:

Plastic & Reconstructive Surgery

Year:

1969

File:

PDF, 81 KB

1969

47

Exercise Caution Using Hepatic Angioembolization in the Stable Trauma Patient

Samuels, Jason M., Carmichael, Heather, Kovar, Alexandra, Urban, Shane, Vega, Stephanie, Velopulos, Catherine, McIntyre, Robert C.

Journal:

Journal of the American College of Surgeons

Year:

2020

File:

PDF, 84 KB

2020

48

Effects of High Doses of A-74273, a Novel Nonpeptidic and Orally Bioavailable Renin Inhibitor

Verburg, Kenneth M., Polakowski, James S., Kovar, Peter J., Klinghofer, Vered, Barlow, Jennifer L., Stein, Herman H., Mantei, Robert A., Fung, Anthony K. L., Boyd, Steven A., Baker, William R., Kleine

Journal:

Journal of Cardiovascular Pharmacology

Year:

1993

File:

PDF, 628 KB

1993

49

Potent and orally bioavailable noncysteine-containing inhibitors of protein farnesyltransferase

David J. Augeri, Dave Janowick, Douglas Kalvin, Gerry Sullivan, John Larsen, Daniel Dickman, Hong Ding, Jerry Cohen, Jang Lee, Robert Warner, Peter Kovar, Sajeev Cherian, Badr Saeed, Haichao Zhang, St

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 269 KB

english, 1999

50

Near infrared spectroscopy of carbon dioxide. II: 16O13C16O and 16O13C18O line positions

Charles E. Miller, Matthew A. Montgomery, Robert M. Onorato, Christopher Johnstone, Thomas P. McNicholas, Brian Kovaric, Linda R. Brown

Journal:

Journal of Molecular Spectroscopy

Year:

2004

Language:

english

File:

PDF, 702 KB

english, 2004

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